ECLIPSE (Phase III)Centre coordonateur

Investigator physician: Pr Pierre OLIVIER

A Multi-Center, Open-Label, Randomized Phase 3 Trial Comparing the Safety and Efficacy of 177Lu-PSMA-I&T versus Hormone Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer

Phase III prospective multicenter, open-label, randomized study evaluating the efficacy and safety of 177Lu-PSMA-I&T versus a change in hormone therapy in men with metastatic castration-resistant prostate cancer (mCPRC).
Patients are randomized to receive 177Lu-PSMA-I&T or hormone therapy respectively. Hormone therapy can be either abiraterone or enzalutamide, depending on the hormone therapy previously received by the patient.

The treatment under study: 177Lu-PSMA-I&T
Study status: Recruiting
Clinical Trial number: NCT05204927